Research indicates that prolonged sedentary behavior, even with regular exercise, elevates the risk of brain shrinkage and cognitive decline, particularly in older adults. The study, tracking participants over seven years, revealed a link between increased sitting time and neurodegenerative changes, irrespective of physical activity levels.source https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/shocking-prolonged-sitting-can-shrink-the-brain-and-even-regular-exercise-wont-compensate-for-it/articleshow/122766392.cms